Serine protease 56 (PRSS56)

About Serine protease 56

Serine protease 56 (PRSS56) is a protein from Homo sapiens identified by UniProt accession P0CW18, 603 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

Target properties

Protein name	Serine protease 56
UniProt accession	P0CW18
Gene	PRSS56
Organism	Homo sapiens
Length	603 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (79)

Diseases linked to this target (Open Targets).

Isolated anophthalmia - microphthalmia · score 0.79
microphthalmia · score 0.61
nanophthalmia · score 0.44
Myopia · score 0.39
refractive error measurement · score 0.38
refractive error · score 0.37
eye measurement · score 0.37
age at onset · score 0.31
Hypermetropia · score 0.31
Abnormality of refraction · score 0.30

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CW18-F1	alphafold	PREDICTED	74.42	—

Amino-acid sequence (603 residues)

MLLAVLLLLP LPSSWFAHGH PLYTRLPPSA LQVLSAQGTQ ALQAAQRSAQ WAINRVAMEI QHRSHECRGS GRPRPQALLQ DPPEPGPCGE RRPSTANVTR AHGRIVGGSA APPGAWPWLV RLQLGGQPLC GGVLVAASWV LTAAHCFVGA PNELLWTVTL AEGSRGEQAE EVPVNRILPH PKFDPRTFHN DLALVQLWTP VSPGGSARPV CLPQEPQEPP AGTACAIAGW GALFEDGPEA EAVREARVPL LSTDTCRRAL GPGLRPSTML CAGYLAGGVD SCQGDSGGPL TCSEPGPRPR EVLFGVTSWG DGCGEPGKPG VYTRVAVFKD WLQEQMSASS SREPSCRELL AWDPPQELQA DAARLCAFYA RLCPGSQGAC ARLAHQQCLQ RRRRCELRSL AHTLLGLLRN AQELLGPRPG LRRLAPALAL PAPALRESPL HPARELRLHS GSRAAGTRFP KRRPEPRGEA NGCPGLEPLR QKLAALQGAH AWILQVPSEH LAMNFHEVLA DLGSKTLTGL FRAWVRAGLG GRHVAFSGLV GLEPATLARS LPRLLVQALQ AFRVAALAEG EPEGPWMDVG QGPGLERKGH HPLNPQVPPA RQP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards