LIM and senescent cell antigen-like-containing…

About LIM and senescent cell antigen-like-containing domain protein 3

LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3) is a protein from Homo sapiens identified by UniProt accession P0CW19, 117 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	LIM and senescent cell antigen-like-containing domain protein 3
UniProt accession	P0CW19
Gene	LIMS3
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

cancer · score 0.01
carcinoma · score 0.01
mesothelioma · score 0.01
Malignant Mesothelioma · score 0.01
infect · score 0.00
infection · score 0.00
azoospermia · score 0.00
Global developmental delay · score 0.00
Abnormal sperm morphology · score 0.00
Timothy syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CW19-F1	alphafold	PREDICTED	73.20	—

Amino-acid sequence (117 residues)

MAFSGRARPC IIPENEEIPR AALNTVHEAN GTEDERAVSK LQRRHSDVKV YKEFCDFYAK FNMANALASA TCERCKGGFA PAETIVNSNG ELYHEQCFVC AQCFQQFPEG LFYEERT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3)