LIM and senescent cell antigen-like-containing…

About LIM and senescent cell antigen-like-containing domain protein 4

LIM and senescent cell antigen-like-containing domain protein 4 (LIMS4) is a protein from Homo sapiens identified by UniProt accession P0CW20, 117 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	LIM and senescent cell antigen-like-containing domain protein 4
UniProt accession	P0CW20
Gene	LIMS4
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

mean corpuscular hemoglobin concentration · score 0.07
mean corpuscular volume · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CW20-F1	alphafold	PREDICTED	72.35	—

Amino-acid sequence (117 residues)

MAFSGRARPC IIPENEEIPR AALNTVHEAN GTEDERAVSK LQRRHSDVKV YKEFCDFYAK FNMANALASA TCERCKGGFA PAETIVNSNG ELYHEQCFVC AQCFQQFPEG LFYEERT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

LIM and senescent cell antigen-like-containing domain protein 4 (LIMS4)