Paraneoplastic antigen-like protein 6A (PNMA6A)

About Paraneoplastic antigen-like protein 6A

Paraneoplastic antigen-like protein 6A (PNMA6A) is a protein from Homo sapiens identified by UniProt accession P0CW24, 399 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Paraneoplastic antigen-like protein 6A
UniProt accession	P0CW24
Gene	PNMA6A
Organism	Homo sapiens
Length	399 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

neoplasm · score 0.01
childhood leukemia · score 0.01
cancer · score 0.01
acute lymphoblastic leukemia · score 0.01
acute myeloid leukemia · score 0.00
Burkitts lymphoma · score 0.00
plasmacytoma · score 0.00
ependymoma · score 0.00
X-linked hyper-IgM syndrome · score 0.00
carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CW24-F1	alphafold	PREDICTED	75.15	—

Amino-acid sequence (399 residues)

MAVTMLQDWC RWMGVNARRG LLILGIPEDC DDAEFQESLE AALRPMGHFT VLGKAFREED NATAALVELD REVNYALVPR EIPGTGGPWN VVFVPRCSGE EFLGLGRVFH FPEQEGQMVE SVAGALGVGL RRVCWLRSIG QAVQPWVEAV RCQSLGVFSG RDQPAPGEES FEVWLDHTTE MLHVWQGVSE RERRRRLLEG LRGTALQLVH ALLAENPART AQDCLAALAQ VFGDNESQAT IRVKCLTAQQ QSGERLSAFV LRLEVLLQKA MEKEALARAS ADRVRLRQML TRAHLTEPLD EALRKLRMAG RSPSFLEMLG LVRESEAWEA SLARSVRAQT QEGAGARAGA QAVARASTKV EAVPGGPGRE PEGLLQAGGQ EAEELLQEGL KPVLEECDN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards