RING finger protein 224 (RNF224)

About RING finger protein 224

RING finger protein 224 (RNF224) is a protein from Homo sapiens identified by UniProt accession P0DH78, 156 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	RING finger protein 224
UniProt accession	P0DH78
Gene	RNF224
Organism	Homo sapiens
Length	156 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

HbA1c measurement · score 0.03
blood pressure · score 0.02
erythrocyte count · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DH78-F1	alphafold	PREDICTED	76.94	—

Amino-acid sequence (156 residues)

MQDAAAGGPP GLGGGGPPEE RTDCIICCSA YDLSGHLPRR LYCGHTFCQA CVRRLDTPAP EQRWIPCPQC RQSTPTPRGG VAMLDLDLAA FLAVKAEREP ARLEPLPLTS LKGSAITRQP AGLCPALGPQ PHFPQPRYCC WGCGSLCCPP LGSPEV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards