Endoregulin (ERLN)

Homo sapiens — UniProt P0DI80

Gene: ERLNHomo sapiensSwissProt reviewed

About Endoregulin

Endoregulin (ERLN) is a protein from Homo sapiens identified by UniProt accession P0DI80, 62 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein nameEndoregulin
UniProt accessionP0DI80
GeneERLN
OrganismHomo sapiens
Length62 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (12)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.27
  • Barrett's esophagus · score 0.04
  • rotator cuff tear · score 0.04
  • COVID-19 · score 0.02
  • ulcerative colitis · score 0.01
  • type 2 diabetes mellitus · score 0.01
  • endometrial carcinoma · score 0.01
  • colorectal cancer · score 0.01
  • Leishmaniasis · score 0.00
  • gastric carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P0DI80-F1alphafoldPREDICTED77.55—

Amino-acid sequence (62 residues)

MDQLVFKETI WNDAFWQNPW DQGGLAVIIL FITAVLLLIL FAIVFGLLTS TENTQCEAGE EE

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Quick facts

UniProtP0DI80
GeneERLN
OrganismHomo sapiens
Length62
Binders0
Diseases12
View on UniProt