About Trafficking protein particle complex subunit 2B
Trafficking protein particle complex subunit 2B (TRAPPC2B) is a protein
from Homo sapiens identified by UniProt accession
P0DI82, 140 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Trafficking protein particle complex subunit 2B |
|---|
| UniProt accession | P0DI82 |
|---|
| Gene | TRAPPC2B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 140 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- platelet count · score 0.05
- snowflake vitreoretinal degeneration · score 0.04
- corneal endothelial dystrophy · score 0.04
- Megalocornea · score 0.04
- megalocornea · score 0.04
- Fuchs endothelial corneal dystrophy · score 0.04
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
- appendicular lean mass · score 0.04
- keratoconus · score 0.04
- Testicular regression syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DI82-F1 | alphafold | PREDICTED | 92.21 | — |
Amino-acid sequence (140 residues)
MSGSFYFVIV GHHDNPVFEM EFLPAGKAES KDDHRHLNQF IAHAALDLVD ENMWLSNNMY LKTVDKFNEW FVSAFVTAGH MRFIMLHDIR QEDGIKNFFT DVYDLYIKFS MNPFYEPNSP IRSSAFDRKV QFLGKKHLLS
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