Protein PET100 homolog, mitochondrial (PET100)

About Protein PET100 homolog, mitochondrial

Protein PET100 homolog, mitochondrial (PET100) is a protein from Homo sapiens identified by UniProt accession P0DJ07, 73 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Disease associations (14)

Diseases linked to this target (Open Targets).

• cytochrome-c oxidase deficiency disease · score 0.69
• mitochondrial complex 4 deficiency, nuclear type 12 · score 0.63
• Leigh syndrome · score 0.55
• leigh syndrome due to mitochondrial complex iv deficiency · score 0.46
• mitochondrial complex IV deficiency, nuclear type 22 · score 0.46
• Intellectual disability · score 0.37
• Seizure · score 0.37
• neurodegenerative disease · score 0.35
• Congenital lactic acidosis · score 0.33
• Abnormality of the mitochondrion · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Amino-acid sequence (73 residues)

External references