About RNA-binding motif protein, Y chromosome, family 1 member A1
RNA-binding motif protein, Y chromosome, family 1 member A1 (RBMY1A1) is a protein
from Homo sapiens identified by UniProt accession
P0DJD3, 496 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | RNA-binding motif protein, Y chromosome, family 1 member A1 |
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| UniProt accession | P0DJD3 |
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| Gene | RBMY1A1 |
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| Organism | Homo sapiens |
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| Length | 496 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (45)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.10
- neoplasm · score 0.07
- cancer · score 0.04
- azoospermia · score 0.01
- bladder transitional cell carcinoma · score 0.01
- Azoospermia · score 0.01
- in situ carcinoma · score 0.01
- chronic obstructive pulmonary disease · score 0.01
- hypospadias · score 0.01
- osteosarcoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DJD3-F1 | alphafold | PREDICTED | 49.60 | — |
Amino-acid sequence (496 residues)
MVEADHPGKL FIGGLNRETN EKMLKAVFGK HGPISEVLLI KDRTSKSRGF AFITFENPAD AKNAAKDMNG KSLHGKAIKV EQAKKPSFQS GGRRRPPASS RNRSPSGSLR SARGSRGGTR GWLPSHEGHL DDGGYTPDLK MSYSRGLIPV KRGPSSRSGG PPPKKSAPSA VARSNSWMGS QGPMSQRREN YGVPPRRATI SSWRNDRMST RHDGYATNDG NHPSCQETRD YAPPSRGYAY RDNGHSNRDE HSSRGYRNHR SSRETRDYAP PSRGHAYRDY GHSRRDESYS RGYRNRRSSR ETREYAPPSR GHGYRDYGHS RRHESYSRGY RNHPSSRETR DYAPPHRDYA YRDYGHSSWD EHSSRGYSYH DGYGEALGRD HSEHLSGSSY RDALQRYGTS HGAPPARGPR MSYGGSTCHA YSNTRDRYGR SWESYSSCGD FHYCDREHVC RKDQRNPPSL GRVLPDPREA CGSSSYVASI VDGGESRSEK GDSSRY
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