GTPase IMAP family member GIMD1 (GIMD1)

About GTPase IMAP family member GIMD1

GTPase IMAP family member GIMD1 (GIMD1) is a protein from Homo sapiens identified by UniProt accession P0DJR0, 217 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	GTPase IMAP family member GIMD1
UniProt accession	P0DJR0
Gene	GIMD1
Organism	Homo sapiens
Length	217 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

balding measurement · score 0.28
hair shape measurement · score 0.14
osteoarthritis · score 0.05
alopecia · score 0.04
systolic blood pressure · score 0.02
FEV/FVC ratio · score 0.02
blood protein measurement · score 0.02
sleep measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DJR0-F1	alphafold	PREDICTED	93.46	—

Amino-acid sequence (217 residues)

MTDPNKMIIN LALFGMTQSG KSSAGNILLG STDFHSSFAP CSVTTCCSLG RSCHLHSFMR RGGLEVALQV QVLDTPGYPH SRLSKKYVKQ EVKEALAHHF GQGGLHLALL VQRADVPFCG QEVTDPVQMI QELLGHAWMN YTAILFTHAE KIEEAGLTED KYLHEASDTL KTLLNSIQHK YVFQYKKGKS LNEQRMKILE RIMEFIKENC YQVLTFK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards