Trophoblast glycoprotein-like (TPBGL)

About Trophoblast glycoprotein-like

Trophoblast glycoprotein-like (TPBGL) is a protein from Homo sapiens identified by UniProt accession P0DKB5, 382 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	Trophoblast glycoprotein-like
UniProt accession	P0DKB5
Gene	TPBGL
Organism	Homo sapiens
Length	382 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

visual perception measurement · score 0.05
ulcerative colitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DKB5-F1	alphafold	PREDICTED	80.28	—

Amino-acid sequence (382 residues)

MAPRAGQPGL QGLLLVAAAL SQPAAPCPFQ CYCFGGPKLL LRCASGAELR QPPRDVPPDA RNLTIVGANL TVLRAAAFAG GDGDGDQAAG VRLPLLSALR LTHNHIEVVE DGAFDGLPSL AALDLSHNPL RALGGGAFRG LPALRSLQLN HALVRGGPAL LAALDAALAP LAELRLLGLA GNALSRLPPA ALRLARLEQL DVRLNALAGL DPDELRALER DGGLPGPRLL LADNPLRCGC AARPLLAWLR NATERVPDSR RLRCAAPRAL LDRPLLDLDG ARLRCADSGA DARGEEAEAA GPELEASYVF FGLVLALIGL IFLMVLYLNR RGIQRWMRNL REACRDQMEG YHYRYEQDAD PRRAPAPAAP AGSRATSPGS GL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards