ARL14 effector protein-like (ARL14EPL)

About ARL14 effector protein-like

ARL14 effector protein-like (ARL14EPL) is a protein from Homo sapiens identified by UniProt accession P0DKL9, 152 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	ARL14 effector protein-like
UniProt accession	P0DKL9
Gene	ARL14EPL
Organism	Homo sapiens
Length	152 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.11
mean corpuscular hemoglobin concentration · score 0.06
central nervous system cancer · score 0.03
musculoskeletal system disease · score 0.03
osteoarthritis, hand · score 0.03
Granulomatosis with Polyangiitis · score 0.02
polycystic ovary syndrome · score 0.00
WAGR syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DKL9-F1	alphafold	PREDICTED	81.85	—

Amino-acid sequence (152 residues)

MNEQSEKNNS IQERHTDHSF PEKNCQIGQK QLQQIERQLK CLAFRNPGPQ VADFNPETRQ QKKKARMSKM NEYFSTKYKI MRKYDKSGRL ICNDADLCDC LEKNCLGCFY PCPKCNSNKC GPECRCNRRW VYDAIVTESG EVISTLPFNV PD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards