Uncharacterized protein C8orf88 (C8orf88)

About Uncharacterized protein C8orf88

Uncharacterized protein C8orf88 (C8orf88) is a protein from Homo sapiens identified by UniProt accession P0DMB2, 117 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Uncharacterized protein C8orf88
UniProt accession	P0DMB2
Gene	C8orf88
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

age at first sexual intercourse measurement · score 0.25
self reported educational attainment · score 0.23
smoking initiation · score 0.21
smoking status measurement · score 0.18
appendicular lean mass · score 0.16
hemoglobin measurement · score 0.13
hematocrit · score 0.11
smoking behaviour measurement · score 0.10
body fat percentage · score 0.03
colorectal cancer · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DMB2-F1	alphafold	PREDICTED	68.11	—

Amino-acid sequence (117 residues)

METKKLIGKP LQPARPVRHL TSPPGAVFPF NFQNEYPCNT QCIQSGVSRC KTNGMQAFSQ GLNEQQQQQS PVKKERIKYS RDFLLKLSSV SICRKKPDFL PDHPIVLQKP ENNQSFK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards