About Chorionic somatomammotropin hormone 1
Chorionic somatomammotropin hormone 1 (CSH1) is a protein
from Homo sapiens identified by UniProt accession
P0DML2, 217 residues long.
MolForge cross-references it against 0 known binders and
73 disease associations.
Target properties
| Protein name | Chorionic somatomammotropin hormone 1 |
|---|
| UniProt accession | P0DML2 |
|---|
| Gene | CSH1 |
|---|
| Organism | Homo sapiens |
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| Length | 217 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (73)
Diseases linked to this target (Open Targets).
- acute lymphoblastic leukemia · score 0.10
- body height · score 0.08
- BMI-adjusted hip circumference · score 0.07
- serum alanine aminotransferase measurement · score 0.06
- bilirubin measurement · score 0.06
- Pituicytoma · score 0.06
- neoplasm · score 0.06
- grip strength measurement · score 0.05
- growth hormone-secreting pituitary adenoma · score 0.05
- Non-acquired isolated growth hormone deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DML2-F1 | alphafold | PREDICTED | 82.14 | — |
Amino-acid sequence (217 residues)
MAPGSRTSLL LAFALLCLPW LQEAGAVQTV PLSRLFDHAM LQAHRAHQLA IDTYQEFEET YIPKDQKYSF LHDSQTSFCF SDSIPTPSNM EETQQKSNLE LLRISLLLIE SWLEPVRFLR SMFANNLVYD TSDSDDYHLL KDLEEGIQTL MGRLEDGSRR TGQILKQTYS KFDTNSHNHD ALLKNYGLLY CFRKDMDKVE TFLRMVQCRS VEGSCGF
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