About Chorionic somatomammotropin hormone 2
Chorionic somatomammotropin hormone 2 (CSH2) is a protein
from Homo sapiens identified by UniProt accession
P0DML3, 217 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Chorionic somatomammotropin hormone 2 |
|---|
| UniProt accession | P0DML3 |
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| Gene | CSH2 |
|---|
| Organism | Homo sapiens |
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| Length | 217 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (72)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- body height · score 0.20
- hematocrit · score 0.11
- hemoglobin measurement · score 0.10
- bilirubin measurement · score 0.10
- neuroimaging measurement · score 0.09
- brain volume measurement · score 0.09
- serum alanine aminotransferase measurement · score 0.07
- mean corpuscular hemoglobin concentration · score 0.07
- BMI-adjusted hip circumference · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DML3-F1 | alphafold | PREDICTED | 82.62 | — |
Amino-acid sequence (217 residues)
MAAGSRTSLL LAFALLCLPW LQEAGAVQTV PLSRLFDHAM LQAHRAHQLA IDTYQEFEET YIPKDQKYSF LHDSQTSFCF SDSIPTPSNM EETQQKSNLE LLRISLLLIE SWLEPVRFLR SMFANNLVYD TSDSDDYHLL KDLEEGIQTL MGRLEDGSRR TGQILKQTYS KFDTNSHNHD ALLKNYGLLY CFRKDMDKVE TFLRMVQCRS VEGSCGF
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