Putative transmembrane protein INAFM2 (INAFM2)

About Putative transmembrane protein INAFM2

Putative transmembrane protein INAFM2 (INAFM2) is a protein from Homo sapiens identified by UniProt accession P0DMQ5, 153 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Putative transmembrane protein INAFM2
UniProt accession	P0DMQ5
Gene	INAFM2
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

type 2 diabetes mellitus · score 0.28
glucose measurement · score 0.19
hemoglobin A1 measurement · score 0.18
HbA1c measurement · score 0.05
Drugs used in diabetes use measurement · score 0.04
body weight · score 0.04
cystatin C measurement · score 0.02
IGA glomerulonephritis · score 0.01
neoplasm · score 0.00
metastatic melanoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DMQ5-F1	alphafold	PREDICTED	58.46	—

Amino-acid sequence (153 residues)

MKERDAAPAE RGKPATYTGD KKAKMAAKTN KKWVRLATVF AYVLSVSLAA IVLAVYYSLI WQPVGAGTSG GAAGPPPGGS NATGPSGTSG AAAAGPNTTG SSRREAPRDV PPLQAARPAP PEPPADSPPA GPLERPRGPD EDEEETAAAP GSR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards