Putative uncharacterized protein C8orf89 (C8orf89)

About Putative uncharacterized protein C8orf89

Putative uncharacterized protein C8orf89 (C8orf89) is a protein from Homo sapiens identified by UniProt accession P0DMQ9, 161 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Putative uncharacterized protein C8orf89
UniProt accession	P0DMQ9
Gene	C8orf89
Organism	Homo sapiens
Length	161 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

diffuse plaque measurement · score 0.24
appendicular lean mass · score 0.10
brain measurement · score 0.08
Varicose veins · score 0.08
Abnormality of refraction · score 0.08
platelet crit · score 0.08
platelet count · score 0.06
peak expiratory flow · score 0.03
cortical thickness · score 0.03
balding measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DMQ9-F1	alphafold	PREDICTED	67.60	—

Amino-acid sequence (161 residues)

MSVLSPEIKC ETSKFTRSSF GSCLIFESSW KKAVLETQKI KKEYTTAFGL EELKECIKMP YLPGLQSCQK SVSSTPLEVP KRLPRADAEV SAVRLKKTKE TCSVAPLWEK SKGSGFSDPL TGAPSQYLER LSKIAILEYD TIRQETTTKS KKSKKRDLRD R

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards