NLR family pyrin domain-containing protein 2B (NLRP2B)

About NLR family pyrin domain-containing protein 2B

NLR family pyrin domain-containing protein 2B (NLRP2B) is a protein from Homo sapiens identified by UniProt accession P0DMW2, 45 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	NLR family pyrin domain-containing protein 2B
UniProt accession	P0DMW2
Gene	NLRP2B
Organism	Homo sapiens
Length	45 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

androgenetic alopecia · score 0.06
balding measurement · score 0.03
non-small cell lung carcinoma · score 0.03
type 2 diabetes mellitus · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DMW2-F1	alphafold	PREDICTED	74.19	—

Amino-acid sequence (45 residues)

MVSSAQLDFN LQALLGQLSQ DDLCKFKSLI RTVSLGNELQ KIPQT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards