About Choriogonadotropin subunit beta 3
Choriogonadotropin subunit beta 3 (CGB3) is a protein
from Homo sapiens identified by UniProt accession
P0DN86, 165 residues long.
MolForge cross-references it against 0 known binders and
280 disease associations.
Target properties
| Protein name | Choriogonadotropin subunit beta 3 |
|---|
| UniProt accession | P0DN86 |
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| Gene | CGB3 |
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| Organism | Homo sapiens |
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| Length | 165 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (280)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- testosterone measurement · score 0.08
- Kallmann syndrome · score 0.07
- isolated congenital hypogonadotropic hypogonadism · score 0.07
- 46,XX gonadal dysgenesis · score 0.07
- azoospermia · score 0.07
- hypogonadotropic hypogonadism · score 0.07
- primary ovarian insufficiency · score 0.07
- Testicular regression syndrome · score 0.06
- 46,XX testicular disorder of sex development · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DN86-F1 | alphafold | PREDICTED | 78.88 | — |
Amino-acid sequence (165 residues)
MEMFQGLLLL LLLSMGGTWA SKEPLRPRCR PINATLAVEK EGCPVCITVN TTICAGYCPT MTRVLQGVLP ALPQVVCNYR DVRFESIRLP GCPRGVNPVV SYAVALSCQC ALCRRSTTDC GGPKDHPLTC DDPRFQDSSS SKAPPPSLPS PSRLPGPSDT PILPQ
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