Coiled-coil domain-containing protein 192 (CCDC192)

About Coiled-coil domain-containing protein 192

Coiled-coil domain-containing protein 192 (CCDC192) is a protein from Homo sapiens identified by UniProt accession P0DO97, 292 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 192
UniProt accession	P0DO97
Gene	CCDC192
Organism	Homo sapiens
Length	292 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

hemoglobin measurement · score 0.46
erythrocyte count · score 0.46
hematocrit · score 0.42
schizophrenia · score 0.40
Red cell distribution width · score 0.37
red blood cell density measurement · score 0.36
fungal infectious disease · score 0.31
mean corpuscular hemoglobin concentration · score 0.28
FEV/FVC ratio · score 0.26
sex hormone-binding globulin measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DO97-F1	alphafold	PREDICTED	73.78	—

Amino-acid sequence (292 residues)

MMPVDVCPRD RGSQWVWLEM GQCYSKKSVV PESDTSERSS MTSGSSESDI PQENKVSKAS LDTGQMAFTL AQLESLEICL KEAEEKAKAL SEQLSVSEGT KSKLLEQVSR LEEKLEAVDH KEASGGPYEK MVLVKDQCIQ KLQAEVKASQ EQLIAQKLKH EKKVKKLQTD LATANAITVL ELNEKIKTLY EGKPAPREDS LLEGFCGGLP PVEEGDRKIS LIMELSTQVS LQTERITQLK EVLEEKERKI QQLEAERSPH PPQEVKDPPG CLPEAPVFST HDIPPVVSDE NL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards