About Immunoglobulin lambda constant 2
Immunoglobulin lambda constant 2 (IGLC2) is a protein
from Homo sapiens identified by UniProt accession
P0DOY2, 106 residues long.
MolForge cross-references it against 0 known binders and
58 disease associations.
Target properties
| Protein name | Immunoglobulin lambda constant 2 |
|---|
| UniProt accession | P0DOY2 |
|---|
| Gene | IGLC2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 106 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | LOW |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (58)
Diseases linked to this target (Open Targets).
- cutaneous Leishmaniasis · score 0.59
- triple-negative breast cancer · score 0.08
- Barrett's esophagus · score 0.07
- neutropenia, severe congenital, 2, autosomal dominant · score 0.06
- squamous cell carcinoma · score 0.06
- sebaceous of Jadassohn nevus · score 0.06
- Okt4 epitope deficiency · score 0.06
- central nervous system cancer · score 0.05
- combined immunodeficiency with skin granulomas · score 0.05
- esophageal adenocarcinoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DOY2-F1 | alphafold | PREDICTED | 95.96 | — |
Amino-acid sequence (106 residues)
GQPKAAPSVT LFPPSSEELQ ANKATLVCLI SDFYPGAVTV AWKADSSPVK AGVETTTPSK QSNNKYAASS YLSLTPEQWK SHRSYSCQVT HEGSTVEKTV APTECS
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