About Calmodulin-1
Calmodulin-1 (CALM1) is a protein
from Homo sapiens identified by UniProt accession
P0DP23, 149 residues long.
MolForge cross-references it against 0 known binders and
296 disease associations.
Target properties
| Protein name | Calmodulin-1 |
|---|
| UniProt accession | P0DP23 |
|---|
| Gene | CALM1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 149 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (2)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (296)
Diseases linked to this target (Open Targets).
- long QT syndrome 14 · score 0.75
- catecholaminergic polymorphic ventricular tachycardia 4 · score 0.69
- cardiovascular disease · score 0.53
- familial long QT syndrome · score 0.47
- catecholaminergic polymorphic ventricular tachycardia · score 0.47
- calcium measurement · score 0.42
- Romano-Ward syndrome · score 0.39
- Prolonged QT interval · score 0.37
- anthrax infection · score 0.37
- catecholaminergic polymorphic ventricular tachycardia 1 · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DP23-F1 | alphafold | PREDICTED | 85.24 | — |
Amino-acid sequence (149 residues)
MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK
Explore Calmodulin-1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets