About Calmodulin-2
Calmodulin-2 (CALM2) is a protein
from Homo sapiens identified by UniProt accession
P0DP24, 149 residues long.
MolForge cross-references it against 0 known binders and
205 disease associations.
Target properties
| Protein name | Calmodulin-2 |
|---|
| UniProt accession | P0DP24 |
|---|
| Gene | CALM2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 149 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (205)
Diseases linked to this target (Open Targets).
- long QT syndrome 15 · score 0.78
- long QT syndrome 1 · score 0.55
- familial long QT syndrome · score 0.47
- Prolonged QT interval · score 0.46
- Romano-Ward syndrome · score 0.39
- sudden infant death syndrome · score 0.33
- catecholaminergic polymorphic ventricular tachycardia · score 0.24
- neurodegenerative disease · score 0.24
- protein measurement · score 0.20
- sleep duration · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DP24-F1 | alphafold | PREDICTED | 85.83 | — |
Amino-acid sequence (149 residues)
MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK
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