About Calmodulin-3
Calmodulin-3 (CALM3) is a protein
from Homo sapiens identified by UniProt accession
P0DP25, 149 residues long.
MolForge cross-references it against 0 known binders and
67 disease associations.
Target properties
| Protein name | Calmodulin-3 |
|---|
| UniProt accession | P0DP25 |
|---|
| Gene | CALM3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 149 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (67)
Diseases linked to this target (Open Targets).
- long QT syndrome 16 · score 0.61
- long QT syndrome 1 · score 0.51
- familial long QT syndrome · score 0.47
- neurodegenerative disease · score 0.37
- Romano-Ward syndrome · score 0.37
- Prolonged QT interval · score 0.37
- P wave terminal force measurement · score 0.32
- Immature Reticulocyte Fraction Measurement · score 0.31
- vital capacity · score 0.30
- C-reactive protein measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DP25-F1 | alphafold | PREDICTED | 85.48 | — |
Amino-acid sequence (149 residues)
MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK
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