About V-set and immunoglobulin domain-containing protein 10-like 2
V-set and immunoglobulin domain-containing protein 10-like 2 (VSIG10L2) is a protein
from Homo sapiens identified by UniProt accession
P0DP72, 767 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | V-set and immunoglobulin domain-containing protein 10-like 2 |
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| UniProt accession | P0DP72 |
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| Gene | VSIG10L2 |
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| Organism | Homo sapiens |
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| Length | 767 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (12)
Diseases linked to this target (Open Targets).
- body height · score 0.29
- holoprosencephaly · score 0.19
- appendicular lean mass · score 0.12
- tooth eruption · score 0.10
- hair shape measurement · score 0.04
- self reported educational attainment · score 0.04
- systolic blood pressure · score 0.04
- FEV/FVC ratio · score 0.04
- balding measurement · score 0.03
- sitting height measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DP72-F1 | alphafold | PREDICTED | 81.47 | — |
Amino-acid sequence (767 residues)
MVGQRAQHSP VSLLLLIHLC LLHLRASGQP HPTPEAPVEE VVSVQGVRGG SVELACGSGP APLLVLWSFT PLGSLVPRPV AVTDGAMSKV EAIASALGVV SLRNSSLVLG ELHEGARGHF LCQVLHVAGG QLHAAYSHLT LAVLVPVSKP QVRLSNPSPV EGASVVATCA VREGTEPVTF AWQHRAPRGL GEALVGVTEP LFQLDPVNRT HLGWYMCSAS NSVNRLSSDG AFLDVIYGPD KPVITMEPLG LTEEGFWASE REEVTLSCLA ASNPPSHYVW LRDHTQVHTG PTYVIARAGR VHTGLYTCLA RNSYLDTRTQ TTVQLTIYYP PEGQPSCAVH PSPEAVTLLC AWPGGLPPAQ LQWEGPQGPG PTAPSNVTWS HAAAQLPSGS VFTCTGQHPA LAPPALCTVM LWEPLGRPTC WSTATMGDQF IMLSCEWPGG EPPATLGWLD EQQQPLGGSS SSMAVHLLQA QEDLAGREFT CRGTHLLRTP DPHCHLQLEA PQLDVAEPRV SVLEGGEAWL ECSLRGGTPP AQLLWLGPQQ QKVDPGTSGF MLHPEGAQLR LGIYDADPAH HRGTYQCVAR NAVGNSSQSV LLEVLRYPAP PNVTISRLTY GRHRREVQLQ WAILGPGNLT GFLVQRKASA LGPGAGAWET AASDIEPESR GRRLGGLDPG VLYAFRILAL NHHTAGHPSE VKIPADPPFS AYPAVLGAAG TGMVVATVAS LLVFQYAARH PETFPRLETP TTTPGLDPAQ ETTDSPVNVT ITVTATP
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