Beta-defensin 130B (DEFB130B)

About Beta-defensin 130B

Beta-defensin 130B (DEFB130B) is a protein from Homo sapiens identified by UniProt accession P0DP73, 79 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Beta-defensin 130B
UniProt accession	P0DP73
Gene	DEFB130B
Organism	Homo sapiens
Length	79 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

hypothyroidism · score 0.08
bone quantitative ultrasound measurement · score 0.04
heel bone mineral density · score 0.03
platelet component distribution width · score 0.02
cholelithiasis · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DP73-F1	alphafold	PREDICTED	82.58	—

Amino-acid sequence (79 residues)

MKLHSLISVL LLFVTLIPKG KTGVIPGQKQ CIALKGVCRD KLCSTLDDTI GICNEGKKCC RRWWILEPYP TPVPKGKSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards