Protein POLR1D, isoform 2 (POLR1D)

Homo sapiens — UniProt P0DPB5

Gene: POLR1DHomo sapiensSwissProt reviewed

About Protein POLR1D, isoform 2

Protein POLR1D, isoform 2 (POLR1D) is a protein from Homo sapiens identified by UniProt accession P0DPB5, 122 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.

Target properties

Protein nameProtein POLR1D, isoform 2
UniProt accessionP0DPB5
GenePOLR1D
OrganismHomo sapiens
Length122 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (58)

Diseases linked to this target (Open Targets).

  • Treacher-Collins syndrome · score 0.70
  • alcohol consumption measurement · score 0.26
  • childhood trauma measurement · score 0.26
  • endometrial cancer · score 0.26
  • type 2 diabetes mellitus · score 0.17
  • genetic disorder · score 0.17
  • neurodegenerative disease · score 0.15
  • mathematical ability · score 0.12
  • Hearing impairment · score 0.12
  • breast adenocarcinoma · score 0.11

3D Structure

Predicted structure for P0DPB5 is available from the AlphaFold Protein Structure Database.

Amino-acid sequence (122 residues)

MEEDQELERK AIEELLKEAK RGKTRAETMG PMGWMKCPLA STNKRFLINT IKNTLPSHKE QDHEQKEGDK EPAKSQAQKE ENPKKHRSHP YKHSFRARGS ASYSPPRKRS SQDKYEKRSN RR

Explore Protein POLR1D, isoform 2 with MolForge

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Quick facts

UniProtP0DPB5
GenePOLR1D
OrganismHomo sapiens
Length122
Binders0
Diseases58
View on UniProt