About EEF1A lysine methyltransferase 4
EEF1A lysine methyltransferase 4 (EEF1AKMT4) is a protein
from Homo sapiens identified by UniProt accession
P0DPD7, 255 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | EEF1A lysine methyltransferase 4 |
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| UniProt accession | P0DPD7 |
|---|
| Gene | EEF1AKMT4 |
|---|
| Organism | Homo sapiens |
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| Length | 255 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- cortical thickness · score 0.14
- mathematical ability · score 0.14
- brain volume measurement · score 0.08
- neuroimaging measurement · score 0.08
- lean body mass · score 0.07
- fat body mass · score 0.06
- body mass index · score 0.06
- base metabolic rate measurement · score 0.05
- whole body water mass · score 0.05
- hypertension · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DPD7-F1 | alphafold | PREDICTED | 90.09 | — |
Amino-acid sequence (255 residues)
MASPGAGRAP PELPERNCGY REVEYWDQRY QGAADSAPYD WFGDFSSFRA LLEPELRPED RILVLGCGNS ALSYELFLGG FPNVTSVDYS SVVVAAMQAR HAHVPQLRWE TMDVRKLDFP SASFDVVLEK GTLDALLAGE RDPWTVSSEG VHTVDQVLSE VSRVLVPGGR FISMTSAAPH FRTRHYAQAY YGWSLRHATY GSGFHFHLYL MHKGGKLSVA QLALGAQILS PPRPPTSPCF LQDSDHEDFL SAIQL
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