Tubulin alpha-3C chain (TUBA3C)

About Tubulin alpha-3C chain

Tubulin alpha-3C chain (TUBA3C) is a protein from Homo sapiens identified by UniProt accession P0DPH7, 450 residues long. MolForge cross-references it against 0 known binders and 117 disease associations.

Target properties

Protein name	Tubulin alpha-3C chain
UniProt accession	P0DPH7
Gene	TUBA3C
Organism	Homo sapiens
Length	450 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (117)

Diseases linked to this target (Open Targets).

viral disease · score 0.46
urinary bladder cancer · score 0.38
lung cancer · score 0.37
fallopian tube neoplasm · score 0.37
malignant epithelial tumor of ovary · score 0.37
peritoneal neoplasm · score 0.37
breast cancer · score 0.37
non-small cell lung carcinoma · score 0.37
neoplasm · score 0.35
neutropenia · score 0.34

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DPH7-F1	alphafold	PREDICTED	92.03	—

Amino-acid sequence (450 residues)

MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVVDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIVDLVLD RIRKLADLCT GLQGFLIFHS FGGGTGSGFA SLLMERLSVD YGKKSKLEFA IYPAPQVSTA VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL IGQIVSSITA SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN QMVKCDPRHG KYMACCMLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE AREDLAALEK DYEEVGVDSV EAEAEEGEEY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards