Centromere protein V-like protein 2 (CENPVL2)

About Centromere protein V-like protein 2

Centromere protein V-like protein 2 (CENPVL2) is a protein from Homo sapiens identified by UniProt accession P0DPI3, 272 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Centromere protein V-like protein 2
UniProt accession	P0DPI3
Gene	CENPVL2
Organism	Homo sapiens
Length	272 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

X-linked intellectual disability · score 0.01
Intellectual disability · score 0.00
Global developmental delay · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DPI3-F1	alphafold	PREDICTED	71.36	—

Amino-acid sequence (272 residues)

MGRVRNRATA QRRRRKRPGD PPAACAAIAV TGASRAQCPR VQVGVGSHAA AKRWLGRWRR KRRWRRVRKA GPRDLLPSAP TPDPPGPAPS PKDLDLGAQR ERWETFRKLR GLSCEGAAKV LLDTFEYPGL VHHTGGCHCG AVRFAVWAPA DLRVVDCSCR LCRKKQHRHF LVPASRFTLL QGAESIVTYR SNTHPALHSF CSRCGVQSFH AAVSDPRVYG VAPHCLDEGT VRSVVIEEVG GGDPGEEAAE EHKAIHKTSS QSAPACPREQ EQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards