Histone H3.Y (H3Y1)

About Histone H3.Y

Histone H3.Y (H3Y1) is a protein from Homo sapiens identified by UniProt accession P0DPK2, 136 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Histone H3.Y
UniProt accession	P0DPK2
Gene	H3Y1
Organism	Homo sapiens
Length	136 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

breast carcinoma · score 0.01
cytomegalovirus infection · score 0.00
neoplasm · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DPK2-F1	alphafold	PREDICTED	84.96	—

Amino-acid sequence (136 residues)

MARTKQTARK ATAWQAPRKP LATKAAGKRA PPTGGIKKPH RYKPGTLALR EIRKYQKSTQ LLLRKLPFQR LVREIAQAIS PDLRFQSAAI GALQEASEAY LVQLFEDTNL CAIHARRVTI MPRDMQLARR LRREGP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards