Histone H3.X (H3Y2)

About Histone H3.X

Histone H3.X (H3Y2) is a protein from Homo sapiens identified by UniProt accession P0DPK5, 147 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Histone H3.X
UniProt accession	P0DPK5
Gene	H3Y2
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.06
reticulocyte measurement · score 0.05
body mass index · score 0.04
monocyte count · score 0.04
viral disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DPK5-F1	alphafold	PREDICTED	82.08	—

Amino-acid sequence (147 residues)

MARTKQTARK ATAWQAPRKP LATKAARKRA SPTGGIKKPH RYKPGTLALR EIRKYQKSTQ LLLRKLPFQR LVREIAQAIS PDLRFQSAAI GALQEASEAY LVQLFEDTNL CAIHARRVTI MPRDMQLARR LRGEGAGEPT LLGNLAL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards