About Proline-rich protein 20G
Proline-rich protein 20G (PRR20G) is a protein
from Homo sapiens identified by UniProt accession
P0DPQ3, 210 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Proline-rich protein 20G |
|---|
| UniProt accession | P0DPQ3 |
|---|
| Gene | PRR20G |
|---|
| Organism | Homo sapiens |
|---|
| Length | 210 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.35
- mathematical ability · score 0.33
- intelligence · score 0.31
- risk-taking behaviour · score 0.29
- cognitive function measurement · score 0.23
- schizophrenia · score 0.22
- cortical surface area measurement · score 0.22
- risky sexual behaviour measurement · score 0.16
- colon adenocarcinoma · score 0.07
- peak expiratory flow · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DPQ3-F1 | alphafold | PREDICTED | 49.86 | — |
Amino-acid sequence (210 residues)
MEEPRHSKRP RFLAPNQASG GPPTEPGCSG VDREDPVDPV QPAKPTAYVK PMRREPPARA QPAPPAGRGQ RGGGSWRAGR GRGSGAGLLR ALGERVGPGM YLVHLNDHGE LGYQGQLEAR QTPAFSFTEA ALMPGIVQEG PGPHAAQPEV GLQEPPPAPG PVAVARQTML APSPSLSFRP PGGSSTLCIV QTSNSTIVQS VPVFPAHSAH
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