About Alpha-amylase 1C
Alpha-amylase 1C (AMY1C) is a protein
from Homo sapiens identified by UniProt accession
P0DTE8, 511 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Alpha-amylase 1C |
|---|
| UniProt accession | P0DTE8 |
|---|
| Gene | AMY1C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 511 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.31
- leukocyte count · score 0.22
- protein measurement · score 0.21
- fatty acid measurement · score 0.17
- dentures · score 0.13
- dental caries · score 0.11
- Malignant Urinary System Neoplasm · score 0.05
- smoking behavior · score 0.04
- type 1 diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0DTE8-F1 | alphafold | PREDICTED | 96.68 | — |
Amino-acid sequence (511 residues)
MKLFWLLFTI GFCWAQYSSN TQQGRTSIVH LFEWRWVDIA LECERYLAPK GFGGVQVSPP NENVAIHNPF RPWWERYQPV SYKLCTRSGN EDEFRNMVTR CNNVGVRIYV DAVINHMCGN AVSAGTSSTC GSYFNPGSRD FPAVPYSGWD FNDGKCKTGS GDIENYNDAT QVRDCRLSGL LDLALGKDYV RSKIAEYMNH LIDIGVAGFR IDASKHMWPG DIKAILDKLH NLNSNWFPEG SKPFIYQEVI DLGGEPIKSS DYFGNGRVTE FKYGAKLGTV IRKWNGEKMS YLKNWGEGWG FMPSDRALVF VDNHDNQRGH GAGGASILTF WDARLYKMAV GFMLAHPYGF TRVMSSYRWP RYFENGKDVN DWVGPPNDNG VTKEVTINPD TTCGNDWVCE HRWRQIRNMV NFRNVVDGQP FTNWYDNGSN QVAFGRGNRG FIVFNNDDWT FSLTLQTGLP AGTYCDVISG DKINGNCTGI KIYVSDDGKA HFSISNSAED PFIAIHAESK L
Explore Alpha-amylase 1C with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets