PTTG1IP family member 2 (PTTG1IP2)

About PTTG1IP family member 2

PTTG1IP family member 2 (PTTG1IP2) is a protein from Homo sapiens identified by UniProt accession P0DTF9, 154 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	PTTG1IP family member 2
UniProt accession	P0DTF9
Gene	PTTG1IP2
Organism	Homo sapiens
Length	154 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

FEV/FVC ratio · score 0.08
systolic blood pressure · score 0.07
pulse pressure measurement · score 0.04
hepatitis B virus infection · score 0.04
hepatocellular carcinoma · score 0.03
attention deficit hyperactivity disorder · score 0.02
antisocial behaviour measurement · score 0.02
substance abuse · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DTF9-F1	alphafold	PREDICTED	61.86	—

Amino-acid sequence (154 residues)

MCWLRAWGQI LLPVFLSLFL IQLLISFSEN GFIHSPRNNQ KPRDGNEEEC AVKKSCQLCT EDKKCVWCSE EKACKKYCFP YFGCRFSSIY WLNCKVDMFG IMMLLLIAVL ITGFVWYCCA YHFYLQDLNR NRVYFYGRRE TVPIHDRSAT VYDE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards