G antigen 1 (GAGE1)

About G antigen 1

G antigen 1 (GAGE1) is a protein from Homo sapiens identified by UniProt accession P0DTW1, 117 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	G antigen 1
UniProt accession	P0DTW1
Gene	GAGE1
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.04
neoplasm · score 0.02
carcinoma of liver and intrahepatic biliary tract · score 0.02
head and neck squamous cell carcinoma · score 0.01
non-small cell lung carcinoma · score 0.01
cancer · score 0.01
papillary thyroid carcinoma · score 0.01
salivary gland cancer · score 0.01
Miyoshi myopathy · score 0.01
nodular goiter · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DTW1-F1	alphafold	PREDICTED	62.46	—

Amino-acid sequence (117 residues)

MSWRGRSTYY WPRPRRYVQP PEMIGPMRPE QFSDEVEPAT PEEGEPATQR QDPAAAQEGE DEGASAGQGP KPEADSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE GEGQSQC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards