Tetrapeptide repeat homeobox protein 2 (TPRX2)

About Tetrapeptide repeat homeobox protein 2

Tetrapeptide repeat homeobox protein 2 (TPRX2) is a protein from Homo sapiens identified by UniProt accession P0DV77, 301 residues long. MolForge cross-references it against 0 known binders and 0 disease associations.

Target properties

Protein name	Tetrapeptide repeat homeobox protein 2
UniProt accession	P0DV77
Gene	TPRX2
Organism	Homo sapiens
Length	301 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0DV77-F1	alphafold	PREDICTED	63.26	—

Amino-acid sequence (301 residues)

MQDPGHLQGP PLALDPPRRQ RQERTVYTES QQKVLEFYFQ KDQYPNYDQR LNLAEMLSLR EQQLQVWFKN RRAKLARERR LQQQPQRVPG QRGRGARAAP LVPVAAASFP GGPEFPQGRG SWISPQPGPW GVLPAAEPKI YSLPRTWGGP ECGTQEGLKA VPAPGPGPIP APIPGPAQIP GPVPGPAPNL GPMSGPLSVS IPGPIPAPIS CPGPIPDPVL GRTLMPGPGS LPTPAPGALW PQSPYASNLS PDTQLYPDFT KLLPLLDRFE ESSLSTTTSQ YKEEDGFVDK NHSVPRSLLD L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards