About Zinc finger protein 875
Zinc finger protein 875 (ZNF875) is a protein
from Homo sapiens identified by UniProt accession
P10072, 659 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Zinc finger protein 875 |
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| UniProt accession | P10072 |
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| Gene | ZNF875 |
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| Organism | Homo sapiens |
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| Length | 659 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- hematocrit · score 0.30
- arthrogryposis multiplex congenita · score 0.12
- fetal akinesia deformation sequence 1 · score 0.12
- fetal akinesia deformation sequence · score 0.12
- diastolic blood pressure · score 0.12
- hemoglobin measurement · score 0.12
- hypertension · score 0.10
- body height · score 0.06
- smoking status measurement · score 0.05
- erythrocyte count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P10072-F1 | alphafold | PREDICTED | 66.10 | — |
Amino-acid sequence (659 residues)
MRVNHTVSTM LPTCMVHRQT MSCSGAGGIT AFVAFRDVAV YFTQEEWRLL SPAQRTLHRE VMLETYNHLV SLEIPSSKPK LIAQLERGEA PWREERKCPL DLCPESKPEI QLSPSCPLIF SSQQALSQHV WLSHLSQLFS SLWAGNPLHL GKHYPEDQKQ QQDPFCFSGK AEWIQEGEDS RLLFGRVSKN GTSKALSSPP EEQQPAQSKE DNTVVDIGSS PERRADLEET DKVLHGLEVS GFGEIKYEEF GPGFIKESNL LSLQKTQTGE TPYMYTEWGD SFGSMSVLIK NPRTHSGGKP YVCRECGRGF TWKSNLITHQ RTHSGEKPYV CKDCGRGFTW KSNLFTHQRT HSGLKPYVCK ECGQSFSLKS NLITHQRAHT GEKPYVCREC GRGFRQHSHL VRHKRTHSGE KPYICRECEQ GFSQKSHLIR HLRTHTGEKP YVCTECGRHF SWKSNLKTHQ RTHSGVKPYV CLECGQCFSL KSNLNKHQRS HTGEKPFVCT ECGRGFTRKS TLSTHQRTHS GEKPFVCAEC GRGFNDKSTL ISHQRTHSGE KPFMCRECGR RFRQKPNLFR HKRAHSGAFV CRECGQGFCA KLTLIKHQRA HAGGKPHVCR ECGQGFSRQS HLIRHQRTHS GEKPYICRKC GRGFSRKSNL IRHQRTHSG
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