About Peptide YY
Peptide YY (PYY) is a protein
from Homo sapiens identified by UniProt accession
P10082, 97 residues long.
MolForge cross-references it against 0 known binders and
247 disease associations.
Target properties
| Protein name | Peptide YY |
|---|
| UniProt accession | P10082 |
|---|
| Gene | PYY |
|---|
| Organism | Homo sapiens |
|---|
| Length | 97 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (247)
Diseases linked to this target (Open Targets).
- Hyperammonemia due to N-acetylglutamate synthetase deficiency · score 0.34
- hyperammonemia due to N-acetylglutamate synthase deficiency · score 0.34
- DNA methylation · score 0.26
- ovarian cancer · score 0.25
- blood protein measurement · score 0.24
- pulse pressure measurement · score 0.16
- apolipoprotein B measurement · score 0.15
- triglyceride measurement · score 0.14
- body height · score 0.13
- sex hormone-binding globulin measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P10082-F1 | alphafold | PREDICTED | 71.31 | — |
Amino-acid sequence (97 residues)
MVFVRRPWPA LTTVLLALLV CLGALVDAYP IKPEAPREDA SPEELNRYYA SLRHYLNLVT RQRYGKRDGP DTLLSKTFFP DGEDRPVRSR SEGPDLW
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