About Adrenodoxin, mitochondrial
Adrenodoxin, mitochondrial (FDX1) is a protein
from Homo sapiens identified by UniProt accession
P10109, 184 residues long.
MolForge cross-references it against 0 known binders and
214 disease associations.
Target properties
| Protein name | Adrenodoxin, mitochondrial |
|---|
| UniProt accession | P10109 |
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| Gene | FDX1 |
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| Organism | Homo sapiens |
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| Length | 184 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (214)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- congenital adrenal hyperplasia · score 0.37
- serum metabolite measurement · score 0.37
- coronary artery disease · score 0.36
- body height · score 0.34
- angina pectoris · score 0.30
- Vasodilators used in cardiac diseases use measurement · score 0.29
- myocardial infarction · score 0.29
- aspirin use measurement · score 0.29
- lean body mass · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P10109-F1 | alphafold | PREDICTED | 76.92 | — |
Amino-acid sequence (184 residues)
MAAAGGARLL RAASAVLGGP AGRWLHHAGS RAGSSGLLRN RGPGGSAEAS RSLSVSARAR SSSEDKITVH FINRDGETLT TKGKVGDSLL DVVVENNLDI DGFGACEGTL ACSTCHLIFE DHIYEKLDAI TDEENDMLDL AYGLTDRSRL GCQICLTKSM DNMTVRVPET VADARQSIDV GKTS
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