Ras-related protein Rap-2a (RAP2A)

About Ras-related protein Rap-2a

Ras-related protein Rap-2a (RAP2A) is a protein from Homo sapiens identified by UniProt accession P10114, 183 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

Target properties

Protein name	Ras-related protein Rap-2a
UniProt accession	P10114
Gene	RAP2A
Organism	Homo sapiens
Length	183 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P10114-F1	alphafold	PREDICTED	91.71	—

Amino-acid sequence (183 residues)

MREYKVVVLG SGGVGKSALT VQFVTGTFIE KYDPTIEDFY RKEIEVDSSP SVLEILDTAG TEQFASMRDL YIKNGQGFIL VYSLVNQQSF QDIKPMRDQI IRVKRYEKVP VILVGNKVDL ESEREVSSSE GRALAEEWGC PFMETSAKSK TMVDELFAEI VRQMNYAAQP DKDDPCCSAC NIQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards