Interleukin-8 (CXCL8)

Homo sapiens — UniProt P10145

Gene: CXCL8Homo sapiensSwissProt reviewed

About Interleukin-8

Interleukin-8 (CXCL8) is a protein from Homo sapiens identified by UniProt accession P10145, 99 residues long. MolForge cross-references it against 0 known binders and 1,954 disease associations.

Target properties

Protein nameInterleukin-8
UniProt accessionP10145
GeneCXCL8
OrganismHomo sapiens
Length99 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Approved drugs hitting this target (5)

DrugCentral-linked approved drugs that act on this protein.

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P10145-F1alphafoldPREDICTED88.03—

Amino-acid sequence (99 residues)

MTSKLAVALL AAFLISAALC EGAVLPRSAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH CANTEIIVKL SDGRELCLDP KENWVQRVVE KFLKRAENS

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Quick facts

UniProtP10145
GeneCXCL8
OrganismHomo sapiens
Length99
Binders0
Diseases1,954
View on UniProt