About Ras-related protein R-Ras
Ras-related protein R-Ras (RRAS) is a protein
from Homo sapiens identified by UniProt accession
P10301, 218 residues long.
MolForge cross-references it against 0 known binders and
147 disease associations.
Target properties
| Protein name | Ras-related protein R-Ras |
|---|
| UniProt accession | P10301 |
|---|
| Gene | RRAS |
|---|
| Organism | Homo sapiens |
|---|
| Length | 218 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (147)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.29
- neurodegenerative disease · score 0.29
- genetic disorder · score 0.27
- pulse pressure measurement · score 0.23
- serum albumin measurement · score 0.23
- diastolic blood pressure · score 0.22
- total blood protein measurement · score 0.22
- Noonan syndrome · score 0.21
- endometrial cancer · score 0.21
- lung adenocarcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P10301-F1 | alphafold | PREDICTED | 85.53 | — |
Amino-acid sequence (218 residues)
MSSGAASGTG RGRPRGGGPG PGDPPPSETH KLVVVGGGGV GKSALTIQFI QSYFVSDYDP TIEDSYTKIC SVDGIPARLD ILDTAGQEEF GAMREQYMRA GHGFLLVFAI NDRQSFNEVG KLFTQILRVK DRDDFPVVLV GNKADLESQR QVPRSEASAF GASHHVAYFE ASAKLRLNVD EAFEQLVRAV RKYQEQELPP SPPSAPRKKG GGCPCVLL
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