Platelet factor 4 variant (PF4V1)

About Platelet factor 4 variant

Platelet factor 4 variant (PF4V1) is a protein from Homo sapiens identified by UniProt accession P10720, 104 residues long. MolForge cross-references it against 0 known binders and 124 disease associations.

Target properties

Protein name	Platelet factor 4 variant
UniProt accession	P10720
Gene	PF4V1
Organism	Homo sapiens
Length	104 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (124)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.48
neutrophil count · score 0.24
total blood protein measurement · score 0.20
head and neck squamous cell carcinoma · score 0.16
growth-regulated alpha protein measurement · score 0.13
gastric adenocarcinoma · score 0.12
CXCL1 measurement · score 0.11
C-X-C motif chemokine 6 measurement · score 0.10
chemokine (C-X-C motif) ligand 1 measurement · score 0.09
leukocyte count · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P10720-F1	alphafold	PREDICTED	77.23	—

Amino-acid sequence (104 residues)

MSSAARSRLT RATRQEMLFL ALLLLPVVVA FARAEAEEDG DLQCLCVKTT SQVRPRHITS LEVIKAGPHC PTAQLIATLK NGRKICLDLQ ALLYKKIIKE HLES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards