About Fibroblast growth factor 6
Fibroblast growth factor 6 (FGF6) is a protein
from Homo sapiens identified by UniProt accession
P10767, 208 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | Fibroblast growth factor 6 |
|---|
| UniProt accession | P10767 |
|---|
| Gene | FGF6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 208 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- cancer · score 0.60
- bone development disease · score 0.59
- female reproductive endometrioid cancer · score 0.50
- ovarian carcinoma · score 0.46
- migraine disorder · score 0.34
- Antimigraine preparation use measurement · score 0.32
- blood phosphate measurement · score 0.30
- breast adenocarcinoma · score 0.30
- endometrial cancer · score 0.30
- phosphorus measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P10767-F1 | alphafold | PREDICTED | 78.26 | — |
Amino-acid sequence (208 residues)
MALGQKLFIT MSRGAGRLQG TLWALVFLGI LVGMVVPSPA GTRANNTLLD SRGWGTLLSR SRAGLAGEIA GVNWESGYLV GIKRQRRLYC NVGIGFHLQV LPDGRISGTH EENPYSLLEI STVERGVVSL FGVRSALFVA MNSKGRLYAT PSFQEECKFR ETLLPNNYNA YESDLYQGTY IALSKYGRVK RGSKVSPIMT VTHFLPRI
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