About Solute carrier family 2, facilitated glucose transporter member 3
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) is a protein
from Homo sapiens identified by UniProt accession
P11169, 496 residues long.
MolForge cross-references it against 0 known binders and
313 disease associations.
Target properties
| Protein name | Solute carrier family 2, facilitated glucose transporter member 3 |
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| UniProt accession | P11169 |
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| Gene | SLC2A3 |
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| Organism | Homo sapiens |
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| Length | 496 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (313)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- Huntington disease · score 0.39
- visual perception measurement · score 0.21
- neoplasm · score 0.11
- glioblastoma multiforme · score 0.10
- oral squamous cell carcinoma · score 0.10
- head and neck squamous cell carcinoma · score 0.09
- chronic obstructive pulmonary disease · score 0.09
- gonorrhea · score 0.08
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P11169-F1 | alphafold | PREDICTED | 90.29 | — |
Amino-acid sequence (496 residues)
MGTQKVTPAL IFAITVATIG SFQFGYNTGV INAPEKIIKE FINKTLTDKG NAPPSEVLLT SLWSLSVAIF SVGGMIGSFS VGLFVNRFGR RNSMLIVNLL AVTGGCFMGL CKVAKSVEML ILGRLVIGLF CGLCTGFVPM YIGEISPTAL RGAFGTLNQL GIVVGILVAQ IFGLEFILGS EELWPLLLGF TILPAILQSA ALPFCPESPR FLLINRKEEE NAKQILQRLW GTQDVSQDIQ EMKDESARMS QEKQVTVLEL FRVSSYRQPI IISIVLQLSQ QLSGINAVFY YSTGIFKDAG VQEPIYATIG AGVVNTIFTV VSLFLVERAG RRTLHMIGLG GMAFCSTLMT VSLLLKDNYN GMSFVCIGAI LVFVAFFEIG PGPIPWFIVA ELFSQGPRPA AMAVAGCSNW TSNFLVGLLF PSAAHYLGAY VFIIFTGFLI TFLAFTFFKV PETRGRTFED ITRAFEGQAH GADRSGKDGV MEMNSIEPAK ETTTNV
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