About Mannose-binding protein C
Mannose-binding protein C (MBL2) is a protein
from Homo sapiens identified by UniProt accession
P11226, 248 residues long.
MolForge cross-references it against 0 known binders and
627 disease associations.
Target properties
| Protein name | Mannose-binding protein C |
|---|
| UniProt accession | P11226 |
|---|
| Gene | MBL2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 248 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (627)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.47
- heel bone mineral density · score 0.44
- bone quantitative ultrasound measurement · score 0.44
- mannose-binding protein C measurement · score 0.44
- bone density · score 0.42
- COVID-19 · score 0.40
- bone fracture · score 0.37
- body height · score 0.35
- dickkopf‐related protein 1 measurement · score 0.34
- protein measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P11226-F1 | alphafold | PREDICTED | 81.55 | — |
Amino-acid sequence (248 residues)
MSLFPSLPLL LLSMVAASYS ETVTCEDAQK TCPAVIACSS PGINGFPGKD GRDGTKGEKG EPGQGLRGLQ GPPGKLGPPG NPGPSGSPGP KGQKGDPGKS PDGDSSLAAS ERKALQTEMA RIKKWLTFSL GKQVGNKFFL TNGEIMTFEK VKALCVKFQA SVATPRNAAE NGAIQNLIKE EAFLGITDEK TEGQFVDLTG NRLTYTNWNE GEPNNAGSDE DCVLLLKNGQ WNDVPCSTSH LAVCEFPI
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