Pregnancy-specific beta-1-glycoprotein 2 (PSG2)

About Pregnancy-specific beta-1-glycoprotein 2

Pregnancy-specific beta-1-glycoprotein 2 (PSG2) is a protein from Homo sapiens identified by UniProt accession P11465, 335 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

Target properties

Protein name	Pregnancy-specific beta-1-glycoprotein 2
UniProt accession	P11465
Gene	PSG2
Organism	Homo sapiens
Length	335 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (68)

Diseases linked to this target (Open Targets).

bone density · score 0.33
urate measurement · score 0.33
blood protein measurement · score 0.20
breast adenocarcinoma · score 0.18
multiple myeloma · score 0.17
head and neck squamous cell carcinoma · score 0.11
low grade glioma · score 0.10
anti-chlamydia trachomatis antibody measurement · score 0.02
birth weight · score 0.02
calf circumference measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P11465-F1	alphafold	PREDICTED	88.03	—

Amino-acid sequence (335 residues)

MGPLSAPPCT EHIKWKGLLV TASLLNFWNL PTTAQVTIEA QPPKVSEGKD VLLLVHNLPQ NLTGYIWYKG QIRDLYHYIT SYVVDGQIII YGPAYSGRET AYSNASLLIQ NVTREDAGSY TLHIIKRGDG TRGVTGYFTF TLYLETPKPS ISSSNLNPRE AMETVILTCD PETPDTSYQW WMNGQSLPMT HRFQLSETNR TLFLFGVTKY TAGPYECEIR NSGSASRSDP VTLNLLHGPD LPRIHPSYTN YRSGDNLYLS CFANSNPPAQ YSWTINGKFQ QSGQNLFIPQ ITTKHSGLYV CSVRNSATGE ESSTSLTVKV SASTRIGLLP LLNPT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards