About Fibroblast growth factor 5
Fibroblast growth factor 5 (FGF5) is a protein
from Homo sapiens identified by UniProt accession
P12034, 268 residues long.
MolForge cross-references it against 0 known binders and
245 disease associations.
Target properties
| Protein name | Fibroblast growth factor 5 |
|---|
| UniProt accession | P12034 |
|---|
| Gene | FGF5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 268 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (245)
Diseases linked to this target (Open Targets).
- cancer · score 0.60
- bone development disease · score 0.60
- trichomegaly · score 0.55
- systolic blood pressure · score 0.50
- diastolic blood pressure · score 0.50
- hair shape measurement · score 0.48
- hypertension · score 0.47
- hair color · score 0.46
- pulse pressure measurement · score 0.45
- balding measurement · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P12034-F1 | alphafold | PREDICTED | 75.68 | — |
Amino-acid sequence (268 residues)
MSLSFLLLLF FSHLILSAWA HGEKRLAPKG QPGPAATDRN PRGSSSRQSS SSAMSSSSAS SSPAASLGSQ GSGLEQSSFQ WSPSGRRTGS LYCRVGIGFH LQIYPDGKVN GSHEANMLSV LEIFAVSQGI VGIRGVFSNK FLAMSKKGKL HASAKFTDDC KFRERFQENS YNTYASAIHR TEKTGREWYV ALNKRGKAKR GCSPRVKPQH ISTHFLPRFK QSEQPELSFT VTVPEKKKPP SPIKPKIPLS APRKNTNSVK YRLKFRFG
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