ADP/ATP translocase 3 (SLC25A6)

About ADP/ATP translocase 3

ADP/ATP translocase 3 (SLC25A6) is a protein from Homo sapiens identified by UniProt accession P12236, 298 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

Target properties

Protein name	ADP/ATP translocase 3
UniProt accession	P12236
Gene	SLC25A6
Organism	Homo sapiens
Length	298 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (2)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (56)

Diseases linked to this target (Open Targets).

influenza · score 0.37
HIV infection · score 0.37
multiple sclerosis · score 0.31
Alzheimer disease · score 0.31
neurodegenerative disease · score 0.31
Parkinson disease · score 0.31
lysosomal storage disease · score 0.31
clear cell renal carcinoma · score 0.26
cancer · score 0.08
neoplasm · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P12236-F1	alphafold	PREDICTED	92.36	—

Amino-acid sequence (298 residues)

MTEQAISFAK DFLAGGIAAA ISKTAVAPIE RVKLLLQVQH ASKQIAADKQ YKGIVDCIVR IPKEQGVLSF WRGNLANVIR YFPTQALNFA FKDKYKQIFL GGVDKHTQFW RYFAGNLASG GAAGATSLCF VYPLDFARTR LAADVGKSGT EREFRGLGDC LVKITKSDGI RGLYQGFSVS VQGIIIYRAA YFGVYDTAKG MLPDPKNTHI VVSWMIAQTV TAVAGVVSYP FDTVRRRMMM QSGRKGADIM YTGTVDCWRK IFRDEGGKAF FKGAWSNVLR GMGGAFVLVL YDELKKVI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards